TMNT: Mutant Melee
- April's adventure mode
- Successfully complete the Ghetto level with Donatello to unlock April's adventure mode.
- Casey Jones' adventure mode
- Successfully complete the Subway level with Raphael to unlock Casey Jones' adventure mode.
- Foot Soldier's adventure mode
- Successfully complete Raphael's adventure mode to unlock Foot Soldier's adventure mode.
- HUN's adventure mode
- Successfully complete Michaelangelo's adventure mode to unlock HUN's adventure mode.
- Shredder's adventure mode
- Successfully complete Donatello's adventure mode to unlock Shredder's adventure mode.
- Splinter's adventure mode
- Successfully complete Leonardo's adventure mode to unlock Splinter's adventure mode.
- Casey Jones' jacket costume
- Successfully complete Casey Jones' adventure mode with April to unlock Casey Jones' jacket costume.
- Casey Jones' red shorts costume
- Successfully complete the Ghetto level with Casey Jones to unlock Casey Jones' red shorts costume.
- Shredder's gold costume
- Successfully complete Shredder's adventure mode to unlock Shredder's gold costume.
- April's Apartment stage
- Successfully complete the April's Apartment 2 level with Donatello to unlock April's Apartment stage.
- Autumn stage
- Successfully complete The Dojo level with Michaelangelo to unlock the Autumn stage.
- Dojo Complete stage
- Successfully complete the Turtle's Lair level with Casey Jones to unlock the Dojo Complete stage.
- Sewer Falls stage
- Successfully complete the Sewer Falls level with Raphael to unlock the Sewer Falls stage.
- Sewers stage
- Successfully complete the Sewers level with Leonardo to unlock the Sewers stage.
- Shredder's Palace Exterior stage
- Successfully complete The Lab 12 level with Leonardo to unlock the Shredder's Palace Exterior stage.
- Subway stage
- Successfully complete the Sparring With Splinter level with Leonardo to unlock the Subway stage.
- Waterfall stage
- Successfully complete the Turtle's Lair level with April to unlock the Waterfall stage.